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Histamine participates in arousal and nervous-system signaling, so anxiety, agitation or sleep disturbance may occur

Li J, Zhao Y, Shi J, Ren Z, Chen F, Tang W

10.4049/jimmunol.179.3.1595 104 HassaneinM.HoeksemaM

1830:3143-3153 (2013) Lu Y, Tonissen KF, Di Trapani G

Potential mechanism of emphysema: alpha-1 proteinase inhibitor recovered from lungs of cigarette smokers contains oxidized methionine and has decreased elastase inhibitory capacity