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180 The embryonic fibroblasts of CITED2 - / - mouse had defective proliferation, senescence-associated cellular morphology and increase in expression of cell growth inhibitors p16 INK4a , p19 ARF , and p15 INK4b

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Oxidative stress is also a natural process, but like inflammation, when its out of control, meaning in this case, when theres an imbalance of free radicals compared to antioxidants in the body, cell and tissue damage can occur

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95% CI, 1.412.75) in the CANVAS CVOT, which overall included 10,142 patients with T2DM and high cardiovascular risk [75]