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Healthcare providers carefully evaluate each patient's situation, considering factors such as comorbid conditions and medication interactions

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Since NEDD4 is a classical E3 ligase targeting PPAR, this modification ultimately promotes PPAR degradation and disrupts fatty acid homeostasis

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doi: 10.1038/jcbfm.2012.128 72 VindegaardNMunoz-BrionesCEl AliHHKristensenLKRasmussenRSJohansenFFet al

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