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PMID: 15 BurkeOSaBCespedesDASechiATostiA

STEER fuels the debate but does not shift the evidence threshold

Safety Considerations and Who Should Start GLP-1 Therapy GLP-1 agonists are contraindicated in personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2

However, the SmPC does include a warning regarding thyroid C-cell tumours observed in rodent studies, though the relevance to humans remains uncertain and no causal relationship has been established in clinical trials

Dado que la calidad del sueo y la recuperacin estn estrechamente relacionadas con los ritmos hormonales, esta sincronizacin temporal es relevante en los modelos de investigacin centrados en la recuperacin