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Randomization and procedures In the initial treatment stage, periodontal infections in all patients were managed using oral hygiene instruction and mechanical debridement

When vitamin B12 is deficient essentially all of the folate becomes trapped as the N 5 -methylTHF (5-methylTHF

Handling: For laboratory use by qualified research professionals only

Gastrointestinal conditions such as pernicious anemia (autoimmune destruction of gastric parietal cells), Crohn's disease, celiac disease, and prior gastric or ileal surgery significantly impair absorption

Statistical analysis Continuous variables were compared by a paired t -test