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[55] A randomized, double-blind, placebo-controlled study from 2006 assigned participants to one of four groups for the 12 week study period besides the placebo group, one got grapefruit juice, another fresh grapefruit, and finally, the fourth group took capsules continuing grapefruit extract

Within the hypothalamus, GLP-1 receptors are concentrated in the arcuate nucleus and paraventricular nucleusregions that integrate peripheral metabolic signals and coordinate feeding behaviour

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