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The difference lies mainly in their approved uses

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Effect of Sodium-Glucose Cotransporter-2 Inhibitors on Aldosterone-to-Renin Ratio in Diabetic Patients With Hypertension: A Retrospective Observational Study

A member of the RAS superfamily, ADP ribosylation factor 6 (ARF6), acts as a downstream of the KRAS/extracellular signal-regulated kinase (ERK) pathway to increase the proliferation and Warburg effect of pancreatic cancer cells