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its role in the context of psoriasis and PsA remains unclear

however, there have been few in vivo and clinical trials

Intestinal epithelial cells, through shedding or exosome excretion, are the primary sources of host-derived miRNAs

Stress-triggered generation of ROS is linked with the stimulation of phytohormones (ABA and JA) mediated signalling transduction, which eventually suppresses the cyclin-dependent protein kinases (CDKs) that themselves regulate the expressions of cyclins or control the post-translational modification (PTMs) of CDKs consequently heading towards cell cycle seizure or exodus from the cell-cycle [134]

Lu et al