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If we could specifically target this enzyme, people should be fine, and it will possibly help them stop smoking or at least decrease their amount of smoking. So far, the researchers have tested their candidate drugs to make sure they dont disrupt other major enzymes that help the body metabolize other substances

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That's because these are "anti-ligature" designs--i.e., a suicidal prisoner cannot get a shoelace around the top of these to hang themselves from