Not to mention the possible permanent lowering of digestive ability once off GLP-1s, along with the return of the body fat lost, if the situation that originally brought about the obesity has not been addressed
These brain regions, with their lack of BBB, are classical entry portals for bloodborne factors into the brain
Persistent or severe symptoms, however, can interfere with hydration, food intake, medication absorption, and normal organ function
However, challenges including high costs exceeding $1000 per month, gastrointestinal side effects, nutritional deficiencies, and low long-term adherence with subsequent weight regain [5] [6] warrant careful consideration
doi: 10.1016/j.molmet.2019.09.010 [DOI] [PMC free article] [PubMed] [Google Scholar] 4.Shah M, Vella A