The negative symptoms in SCZ may be the result of abnormalities in multiple neural networks (e.g., frontal-cortical-temporal, cortical-striatal
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138 (the Minimum Age Convention), which sets the basic minimum age for employment at 15, and states that children ages 13 to 15 may participate only in light work that is not likely to be harmful to their health or development or hinder their education.[210] The Minimum Age Convention also prohibits children under 18 from engaging in hazardous work.[211] The Minimum Age Convention specifies that children ages 16 and 17 may be authorized to engage in hazardous work on condition that the health, safety and morals of the young persons concerned are fully protected and that the young persons have received adequate specific instruction or vocational training in the relevant branch of activity.[212] ILO Recommendation 190 supports the same principle with regard to the Worst Forms of Child Labour Conventions prohibition on hazardous work for children.[213] Indonesia has also ratified the Convention on the Rights of the Child (CRC), which provides that children have a right to be protected from economic exploitation and from performing any work that is likely to be hazardous or to interfere with the child's education, or to be harmful to the child's health or physical, mental, spiritual, moral or social development.[214] Under the convention, governments must take appropriate legislative, administrative, social, and educational measures to protect children from exploitative and hazardous work, including by establishing a minimum age for employment, regulating the hours and conditions of childrens work, and providing for appropriate penalties or other sanctions to ensure the effective enforcement of such protections.[215] International human rights instruments recognize the right of children to the highest attainable standard of health.[216] The International Covenant on Economic Social and Cultural Rights (ICESCR), ratified by Indonesia in 2006, obligates governments to take the steps necessary for the prevention, treatment and control of occupational and other diseases,[217] and recognizes the right of everyone to the enjoyment of just and favorable conditions of work including safe and healthy working conditions.[218] Governments have the obligation to improve all aspects of environmental and industrial hygiene, for example, through preventive measures to avoid occupational accidents and diseases, and the prevention and reduction of the populations exposure to harmful substances such as harmful chemicals that directly or indirectly impact upon human health.[219] Governments also have a duty to protect human rights in the context of business activity, including commercial agriculture, through effective regulation.[220] The UN Guiding Principles on Business and Human Rights state that this requires taking appropriate steps to prevent, investigate and redress such abuse through effective policies, legislation, regulations and adjudication.[221] Governments also have a duty to effectively enforce that legal and regulatory framework once it is in place, to prevent abuse and ensure accountability and redress for abuses that do occur
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"It's very difficult to defend the existence of an infinite value for some of these brands in the US," he said
