dementia glp-1 Agonists and GLP-1R agonists protect against Alzheimer's

As has been suggested before, it could be that glucagon offers an additional redundant signal that allows for fine-tuning of glucose control in the face of metabolic stress whether it is exercise, hypoglycemia, or postprandial glucose control

Overall, this seems to have a positive effect, Ali says

Recent multisociety practice guidelines have offered more clarity for clinicians who provide sedation outside the operating roomincluding dentists, endoscopists, and proceduralistswhen treating patients on GLP-1 receptor agonists (GLP-1 RAs) like Semaglutide, Ozempic, or Wegovy.sciencedirect Key Recommendations: Shared Decision-Making: Management should involve the patient and all relevant care teams (procedural, anesthesia, prescribing), considering metabolic needs and individual risk factors

They are exploring whether the two systems are linked or separate

Jeek P, Holendov B, Jabrek M, et al