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They cause oxidative stress that can speed up the appearance of ageing signs like wrinkles, dullness , fine lines, and an uneven skin tone

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In vitro studies have demonstrated that when L02 cells were cultured with varying concentrations of catalpol for 24 h, CCK-8 assays revealed no noticeable toxicity at concentrations below 100 mol/L (Pang, 2023)

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