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Following administration of a combined oral contraceptive (0.035 mg ethinyl estradiol and 0.25 mg norgestimate) in the presence of a single dose of tirzepatide 5 mg, mean Cmax of ethinyl estradiol, norgestimate, and norelgestromin was reduced by 59%,66%, and 55%, while mean AUC was reduced by 20%, 21%, and 23%, respectively
Potential Benefits & Side Effects What short pharmacology and animal studies describe
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Dose calculations at 10,000 mcg/mL: 1mg dose = 0.1mL = 10 units on U-100 syringe 2mg dose = 0.2mL = 20 units 4mg dose = 0.4mL = 40 units 6mg dose = 0.6mL = 60 units 8mg dose = 0.8mL = 80 units 12mg dose = 1.2mL = 120 units (requires two draws or larger syringe) This concentration works well for lower and mid-range doses
