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The GLP-1 receptor agonist market is still primarily anchored in type 2 diabetes management, where these drugs improve glycemic control, reduce HbA1c levels, and mitigate cardiovascular risks

Similarly, the blockade of GLP-1R in the PVH with antagonists failed to attenuate liraglutide-induced weight loss [57]

An investigation of the safety and pharmacokinetics of the novel TRPV1 antagonist XEN-D0501 in healthy subjects