When MTX levels become toxic, leucovorin treatment can rescue bone marrow and intestinal epithelial cells by allowing DNA replication to resume
To address this, providers sometimes recommend a daily multi-vitamin, especially if the children: Have self-restricted diets Follow a specific diet (for example, if a child is consuming a diet free of casein, a multi-vitamin may be necessary to ensure adequate vitamin D and calcium intake.) Have chronic diarrhea, constipation, or gastrointestinal inflammation The use of mega-dose vitamins and nutritional supplements beyond a multi-vitamin are not fully supported for routine use
Lyophilized peptides tolerate temperature excursions much better than reconstituted solutions
It is a sulfur-containing amino acid that acts as a stabilizer for the formation of protein structures, and is also necessary for the formation of glutathione.* Selenium is an essential trace mineral that facilitates the production of several important enzymes.*
10.1080/21678421.2017.1363780 104 EhrhartJ.SmithA
