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Essential cofactor for collagen synthesis
More lines of evidence concerning the relationship between H2O2 and Ca2+ signals were provided by the study of H2O2 homeostasis in Arabidopsis (Yang and Poovaiah, 2002)
Critical safety considerations for laboratory use include potential immunogenicity concernswith peptide therapeutics commonly showing injection site reactions (20-40% with subcutaneous administration) and possible antidrug antibody formationalong with theoretical concerns that pro-angiogenic properties could potentially influence experimental tumor models, requiring appropriate controls in oncology-related research
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