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Diarrhea: Diarrhea is another common gastrointestinal side effect of GLP-1 medications, characterized by loose or watery stools

Reversal of selective toxicity of (-)-alpha-lipoic acid by thiamine in thiamine-deficient rats

Genetic variants in CYP3A4, CYP2C19, and GLP1R can predispose some patients to slower drug metabolism, heightened nausea sensitivity, or reduced medication efficacy

While these reactions are not extremely common, they do occur in a notable number of cases

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