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Tobacco harm reduction strategies focus on helping those who cannot quit entirely to reduce harm but do not endorse continued smoking as safe or healthy

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Of those who quit or tried to quit smoking in the past three years, only 30% reported having used cessation aids, such as counseling and pharmacotherapy, to assist their efforts at quitting

The role of smoking cessation is still unclear, but appears to provide some protective effect

Unlike some smoking cessation treatments that significantly affect liver enzymes or interact with numerous drugs, varenicline has few clinically significant drug interactions, making it suitable for people taking multiple medications