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Research suggesting individual aging trajectories must be taken into account when prescribing GLP-1 therapies

This binding prevents rapid renal filtration, creates a slow-release reservoir of active compound, and extends circulation time substantially compared with unmodified peptides

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Other notable adverse effects include injection site reactions (redness, itching, or swelling at the injection site), fatigue, and decreased appetite

However, this medication is only appropriate for patients with these specific genetic conditions and is not indicated for general weight management