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Some medications are approved for other conditions but also help manage weight

Still, available evidence primarily includes retrospective observational studies, many of which rely on analysis of electronic health records and administrative claims data and are subject to limitations

However, individual case reports and patient forums describe back discomfort emerging during Zepbound treatment

10.1046/j.1464-5491.1999.00081.x

Less common, more critical The serious side effects listed in the safety warnings for semaglutide and tirzapetide include changes in vision, while tirzapetide lists the possibility of diabetic retinopathy complications