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Patients should be alert to symptoms such as severe upper abdominal pain (potentially radiating to the back), fever, jaundice, or persistent vomiting, which require urgent medical assessment

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Oxidative imbalance is involved in several models of cancer-induced cachexia [5052], and proteins are major targets of oxidative stress-derived effects on tissues [50, 53]

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Early Phase (Weeks 1 to 3) The first few weeks often produce subtle changes that are easy to overlook