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As such, secondary outcomes include changes in cognition, disease severity and function before and after treatment and across the one-year study period and measures of senescence and AD biomarkers in CSF pre- and post-treatment (baseline and three months) with an optional end of study collection

Statistical analyses were performed using either an un-paired t -test assuming equal variance, one-, or two-way ANOVA, as appropriate, and are specifically indicated on each figure legend

Trimethylamine is also an important gut microbiota-dependent metabolite that is associated with an increased risk of cardiovascular disease

We only accept patients with a BMI of under 30

Meaningful weight loss typically requires 3-6 months of therapy at therapeutic doses