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No significant changes in plasma ALT, -GT and creatinine were observed during the 13 weeks of berberine treatment

PEGylated LPs are an alternative strategy due to the protection afforded by non-specific plasma protein absorption and its uptake in the reticuloendothelial system, resulting in extended systemic circulation and improved biodistribution in the brain

However, this observation remains controversial

APACHE II score as predictors of severe acute biliary pancreatitis

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