Overall, glutathiones neuroprotective efficacy in the CNS is intricately regulated by enzyme expression, metabolic substrate availability, and regional brain biochemistry, making it a pivotal target for intervention in oxidative stress-related neuropathologies
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Serum levels of adiponectin (Millipore, Danvers, MA, USA), ALT, aspartate aminotransferase (AST) (Asan Pharm., Seoul, Korea), and insulin (Mercodia, Uppsala, Sweden) were determined, and the insulin sensitivity index (HOMA-IR=glucoseinsulin/22.5) was also calculated
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Readers are encouraged to consult recent literature for in-depth reviews [128]