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The body naturally possesses a ferroptosis defense system to protect cells, which primarily includes 1) Cystine/System Xc/GSH/GPX4, 2) FSP1-CoQ10-NAD(P)H, 3) DHODH-CoQ10-CoQH2, 4) GCH1/BH4/DHFR, and 5) FSP1/ESCRT-III ( There is hope that increasing ferroptosis in TNBC could improve the effective treatment rate

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