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At present, for high-risk groups of sarcopenia with complex conditions such as chronic kidney disease, liver disease or inflammatory bowel disease, there is still a lack of relevant evidence-based evidence, which makes it difficult for clinicians to precisely balance the significant metabolic benefits and potential risks to muscle health and tolerance when prescriming [65]

Retatrutide is an investigational GLP-1, GIP, and glucagon receptor triple agonist developed by Eli Lilly

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