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The triple agonist approach may offer enhanced weight loss benefits compared to existing GLP-1 medications like Ozempic (semaglutide) or Mounjaro (tirzepatide)
Retrieved from Wharton, S., Lingvay, I., Bogdanski, P., et al
no associations in UC No consistent relationship between BMI and disease complications in CD But in UC there was associated increased risk of needed steroids and hospitalisation, but no impact on surgery California study showed no associated between BMI on hospitalisation or surgery or serious infection (Gu P Am J Gastro 2022) How does obesity impact IBD therapy
In fact, the expression of GLP-1R mRNA in the pituitary was lower than in the hypothalamus and even declined during the estrous cycle [35]