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Transmission electron microscopy has also shown that pregnant women with PCOS have reduced mitochondrial volume, concentrated mitochondrial membrane density, no mitochondrial ridge, and ruptured mitochondrial outer membrane (key characteristics of mitochondrial morphological changes during ferroptosis)

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doi: 10.3389/fphar.2023.1327230 [DOI] [PMC free article] [PubMed] [Google Scholar] 17.Kwon DH, Vasoya M, Sankaranarayanan D

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Key biomarkers for ferroptosis-inducing strategies include malondialdehyde (MDA) and 4-Hydroxynonenal (4-HNE), BODIPY 581/591 C11, and arachidonoyl- and Adrenoyl-Phosphatidylethanolamines (AA-PE and AdA-PE)