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Immunologically, L-citrulline metabolism participates in macrophage response modulation (69), with its intracellular concentrations being dynamically regulated by immune stimuli such as interferon- (IFN-) and lipopolysaccharide (LPS) ( Figure 2d ) ( Figure 2f ) (70)

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And when you lose weight fast without enough protein, your body doesnt only burn fat it burns muscle