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g , Violin plots showing relative fold change (log 2 ) in IP protein abundance associated with indicated organelles from HEK293T cells expressing ER-tag compared to those expressing control-tag

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In patients with locally advanced, metastatic, and/or refractory solid tumors and hematological malignancies, CB839 is being evaluated in open-label phase I clinical trials (NCT02071862, NCT02071888, NCT02771626)