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The hippocampus displays microglial activation, elevated IL-6 and tumor necrosis factor alpha (TNF-), as well as neurotrophic factor signaling disturbances in APP1/PS1 mice with anxiety-like phenotypes (Gao et al., 2018)

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HELPS ATTENUATE MUSCLE FATIGUE: It is a well-established fact that contracting skeletal muscles produce free radicals and the increased production of reactive oxygen species is linked with muscle fatigue