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Our experience shows that researchers often begin with a lower concentration, such as 1-2 M, and then gradually increase it to observe dose-dependent effects

co-supplementation with folic acid and vitamin B 12 (500 g/day) provided an additional 7% reduction (32% decrease) in blood homocysteine concentrations (29)

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Its important because vitamin B12 is integral for many functions, including optimized cell reproduction, blood formation, protein, and tissue synthesis