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The distinctive value of PET imaging lies in its capacity to provide non-invasive, visual evidence of neuroinflammation, thereby directly linking peripheral immune activation with central clinical manifestations, such as brain fog and cognitive decline, while also revealing the heterogeneity within patient populations

(PubMed) Kalim S, Clish CB, Wenger J, et al

Talasaz A, Sadeghipour P, Ortega-Paz L, Kakavand H, Aghakouchakzadeh M, Beavers C, Fanikos J, Eikelboom J, Siegal D, Monreal M, Jimenez D, Vaduganathan M, Castellucci L, Cuker A, Barnes G, Connors J, Secemsky E, Van Tassell B, De Caterina R, Kurlander J, Aminian A, Piazza G, Goldhaber S, Moores L, Middeldorp S, Kirtane A, Elkind M, Angiolillo D, Konstantinides S, Lip G, Stone G, Cushman M, Krumholz H , Mehran R, Bhatt D, Bikdeli B

Glucagon measured by immunoassay Briefly, samples were incubated with two manufacturer-supplied anti-glucagon monoclonal antibodies that were covalently linked to either SmBiT or LgBiT