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As a redox-active cofactor, BH4 directly scavenges PL-OOHs and indirectly promotes CoQ10 biosynthesis, thus conferring resistance to ferroptosis (Wang et al., 2024)
These endometrial tissues can be seeded on the peritoneal cavity, ovaries, and fallopian tubes, as well as distant tissues and organs [2]
NS and SK wrote sections of the manuscript
Beyond its central mitochondrial-mediated effects, Ashwagandhas anticancer activity is further enhanced through multiple mechanisms, including inhibition of angiogenesis, suppression of metastasis, induction of cell cycle arrest, disruption of mitosis via Withanones interaction with the TPX2-Aurora A complex, and impairment of cellular energy metabolism through inhibition of succinate dehydrogenase [94, 98, 219, 220]
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