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Acute Maternal Oxidant Exposure Causes Susceptibility of the Fetal Brain to Inflammation and Oxidative Stress

They are not, however, the same as controlled clinical trials in human subjects

The cataplerotic reactions that involve conversion of PEP to pyruvate in the cytosol then pyruvate to oxaloacetate (OAA) then OAA to aspartate in the mitochondria then aspartate back to OAA in the cytosol and OAA back to PEP constitute what is referred to as pyruvate cycling

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Still, Nrf2-deficient mice display age-dependent cardiomyopathy (87)