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Description

The BMJ, 386, q1645

And the solution is simpler than you think

The mechanisms involve multiple levels: in peripheral tissues, chronically elevated BCAAs and their metabolites may interfere with insulin signaling

The most notable pancreatic PGDP is glucagon, whereas the L cells produce several structurally related peptides, including glucagon-like peptide (GLP)-1 and GLP-2, as well as glicentin and oxyntomodulin, which contain glucagon sequence in their molecules