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Type 2 diabetes in adults: management (NG28) Initial medicines chapter

You should consult your GP if you experience: Persistent difficulty managing blood glucose despite lifestyle modifications Unexplained weight gain or inability to lose weight despite sustained efforts Symptoms of diabetes (excessive thirst, frequent urination, unexplained fatigue) Family history of type 2 diabetes combined with other risk factors Important safety considerations : GLP-1 receptor agonists are prescription medications with potential adverse effects, most commonly gastrointestinal symptoms (nausea, vomiting, diarrhoea)

Barlowe TS, Anderson C, Sandler RS, Subramaniam D, Muratore A, Buse JB, et al