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Most pharmacies assign BUDs between 30 and 90 days, and once the vial is punctured, the practical limit is typically 28 days regardless of the original BUD

Do not heat the vial using warm water, a microwave, or any external heat source, as these can create localized hot spots that damage the peptide even if the overall solution temperature seems reasonable

You continue the medication as long as it remains effective and tolerable

For a complete breakdown of foods that cause the most problems, check our guide on foods to avoid on semaglutide

During this process, the pancreas produces insulin, which helps deliver the sugar molecules from your bloodstream to your cells