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This severe metabolic inflexibility directly contributes to the debilitating phenomenon of post-exertional malaise (PEM), where patients experience a massive, multi-day crash in symptoms following minor physical or cognitive exertion, effectively trapping them in a cycle of energy debt

Son SW, Lee HY, Moeng S, Kuh HJ, Choi SY, Park JK (2020) Participation of microRNAs in the treatment of cancer with phytochemicals

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They need to consider fortified foods or supplements to meet their needs