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This animal model is expected to be a useful tool for investigating the mechanisms of fibrosis in endometriosis and for developing therapeutic strategies to suppress fibrosis

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After menopause, women tend to have lower activity of enzymes involved in glutathione production compared to before menopause

However, it has been recently described that mTORC2 also possesses tyrosine phosphorylation capacity [118], and that it phosphorylates tyrosines on IRS and tyrosine kinases in both receptors, IGF-1 and IR, thus reinstituting the signal of the activated receptors [118]

Gpx4 protects mitochondrial ATP generation against oxidative damage