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Discussion This observational cohort study describes real-world utilization patterns and characteristics of patients dispensed an SGLT2i or GLP-1 RA in the US using data from Optum CDM in the period following changes to the landscape for treatment and prevention of CKD in type 2 diabetes (later period, July 2021September 2023) as well as temporal changes in utilization and baseline characteristics relative to the period prior (earlier period, January 2012June 2021)

Liraglutide for patients with non-alcoholic steatohepatitis

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GLP-1 and Inflammation: A Deeper Look Beyond Weight Loss Discover the surprising scientific link between GLP-1s, your immune system, and a healthier metabolic future

16 However, a portion of spending on these therapies is expected to persist for the non-weight loss indications (e.g., major adverse cardiovascular events [MACE], metabolic dysfunction associated steatohepatitis [MASH], and obstructive sleep apnea [OSA])