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This is a common claim in microdosing communities, and the logic is plausible but unproven
From their beginnings as a treatment for type 2 diabetes, GLP-1 receptor agonists such as the semaglutide drugs Ozempic and Wegovy and the tirzepatide drugs Mounjaro and Zepbound have seen an explosion in use, most popularly for weight loss
Therefore, more specific GST inhibitors may eliminate some of these undesirable features
10.1016/j.alit.2023.12.002 55
It is also worth noting that clinical trial populations are carefully selected and monitored participants with significant pre-existing gastrointestinal disease are typically excluded and real-world rates of nausea may differ once a medicine reaches broader clinical use
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