All enzymatic systems show more enhanced activity in the population without Down syndrome than in the children with Down syndrome, however, there was no statistically significant difference between the two groups
Wu C, Ivars F, Anderson P, Hallmann R, Vestweber D, Nilsson P, Robenek H, Tryggvason K, Song J, Korpos E, et al
For example, dasatinib and quercetin reduce SASP cytokines by promoting apoptosis of ROS-rich senescent cells, while fisetin decreases oxidative stress burden and downregulates NF-B signaling, thereby dampening SASP output
The main takeaway is that glutathione isnt just a general antioxidant
Ive felt no side effects, but truth be told, Ive felt no difference in my appetite either