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Contraindications remain somewhat speculative given limited human data

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But vitamin B12 deficiency stands out because a) its very common experts have estimated that up to 20% of older adults may be low in this vitamin and b) its often missed by doctors

That's why it's important to let your doctor know if you have any of the following conditions before you're prescribed hydroxocobalamin: If you've had an allergic reaction to hydroxocobalamin or any other medicines in the past If you've been diagnosed with low levels of potassium If you have an irregular or fast heartbeat Once you've started taking hydroxocobalamin, you may have some side effects such as pain, swelling, or itchy skin at the point where the syringe was injected