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(2020) conducted a study in which the methanolic root extracts of Colebrookea oppositifolia Smith was subjected to an anticonvulsant activity-guided isolation process, leading to the identification of AC as a potent anticonvulsant compound (Viswanatha et al

Anal Bioanal Chem 414(15):44274439 Papadopoulou A et al (2022) Synthesis, characterization and evaluation of aqueous Zn-based quantum dots for bioapplications

It is now firmly established that the endothelial cells comprising the BBB create a selectively permeable barrier, facilitating the passage of essential nutrients from the bloodstream to the brain while effectively blocking the entry of potentially harmful substances into the brain parenchyma[14]

However, more prospective studies are required to evaluate the effect of other nutrients on migraine patients

Marketing claims promote rapid action despite the 15-minute half-life and poor sustained efficacy documented in trials