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Whereas inflammation is important for tissue regeneration and wound healing, the profound and sustained inflammatory response associated with asthma may result in airway remodeling that involves smooth muscle hypertrophy, epithelial goblet-cell hyperplasia, and permanent deposition of airway extracellular matrix proteins

Bai L, Kong M, Duan Z, Liu S, Zheng S, Chen Y

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Pyruvate is irreversibly converted to acetyl-CoA by pyruvate dehydrogenase (PDH) in the mitochondria

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