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In a recent large cross-sectional study evaluating 9823 T2DM patients from around the world (including Brazil), 34.8% of patients had established cardiovascular disease (CVD), of whom 85.8% had atherosclerotic cardiovascular disease (ASCVD) [8]

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FIGURE 1 Generally, HSP70 binding sites in polypeptide chains repeat every 36 residues, mainly in -sheets with four to five residues, such as leucine, isoleucine, valine, phenylalanine, and tyrosine (Rdiger et al., 1997)