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doi:10.1038/nn0507-535

Fasting, single-food diets and highly restrictive routines: risks and profiles to avoid Intermittent fasting may be suitable for some people, but it is neither universal nor automatically beneficial

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Silibinin has been proven to inhibit the upregulation of co-stimulatory molecules and major histocompatibility complex (MHC) class II molecules on lipopolysaccharide (LPS) stimulated mature DCs, while also suppressing the release of pro-inflammatory cytokines IL-12, IL-23, and TNF-, as well as CD4 + T cell proliferation and Th1/Th17 function, indicating strong immunosuppressive activity (112)

pilot study (BMC Gastroenterol, 2017, PMC5548760) found that 300 mg/day oral glutathione for 4 months reduced ALT and liver fat markers in 29 NAFLD patients