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Specifically, upregulation of the CCR8 signaling pathway promotes the activation of Tregs, reinforcing immunosuppression in the TME and disrupting the dynamic balance between Th17 and Treg cells (80)

375 HSP27 modulators HSP27 modulation has also shown therapeutic promise

Reference : Ryakhovsky, V

Null mutation of the prolactin receptor gene produces multiple reproductive defects in the mouse

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